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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RB1
All Species:
15.76
Human Site:
Y424
Identified Species:
28.89
UniProt:
P06400
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P06400
NP_000312.2
928
106159
Y424
K
R
V
K
D
I
G
Y
I
F
K
E
K
F
A
Chimpanzee
Pan troglodytes
XP_509777
1075
122190
Y571
K
R
V
K
D
I
G
Y
I
F
K
E
K
F
A
Rhesus Macaque
Macaca mulatta
XP_001100383
928
106126
Y424
K
R
V
K
D
I
G
Y
I
F
K
E
K
F
A
Dog
Lupus familis
XP_534118
897
103170
Y393
K
R
V
K
D
V
G
Y
I
F
K
E
K
F
A
Cat
Felis silvestris
Mouse
Mus musculus
P13405
921
105320
H418
K
R
V
K
D
V
G
H
I
F
K
E
K
F
A
Rat
Rattus norvegicus
P33568
920
105007
H417
K
R
V
K
D
V
G
H
I
F
K
E
K
F
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514098
917
104520
C415
K
R
V
E
T
I
G
C
I
F
K
E
K
F
A
Chicken
Gallus gallus
Q90600
921
104417
H414
K
R
V
E
S
L
G
H
I
F
K
K
K
F
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001071248
903
102339
E410
K
R
V
E
E
L
G
E
V
F
I
Q
R
F
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_395096
1006
113492
E431
T
K
V
K
E
L
G
E
Q
F
C
A
N
Y
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_790323
774
86478
S281
P
K
M
E
H
L
E
S
S
Y
H
Q
M
Y
Q
Poplar Tree
Populus trichocarpa
B9GLX8
1035
114624
E482
R
R
A
Q
I
I
L
E
A
I
F
P
S
S
S
Maize
Zea mays
Q3LXA7
1010
111475
G467
H
R
A
G
I
I
L
G
A
I
F
T
S
S
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.2
99.3
90
N.A.
90.4
89.7
N.A.
81.3
73
N.A.
53.9
N.A.
N.A.
23
N.A.
26.4
Protein Similarity:
100
86.3
99.5
93
N.A.
94.9
95.1
N.A.
88.2
84.1
N.A.
70.9
N.A.
N.A.
42.9
N.A.
42.6
P-Site Identity:
100
100
100
93.3
N.A.
86.6
86.6
N.A.
80
66.6
N.A.
46.6
N.A.
N.A.
26.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
86.6
93.3
N.A.
86.6
N.A.
N.A.
53.3
N.A.
46.6
Percent
Protein Identity:
22.1
23.2
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
40.4
42.1
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
33.3
20
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
0
0
0
0
0
16
0
0
8
0
0
70
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
8
0
0
0
0
% C
% Asp:
0
0
0
0
47
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
31
16
0
8
24
0
0
0
54
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
77
16
0
0
70
0
% F
% Gly:
0
0
0
8
0
0
77
8
0
0
0
0
0
0
0
% G
% His:
8
0
0
0
8
0
0
24
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
0
16
47
0
0
62
16
8
0
0
0
0
% I
% Lys:
70
16
0
54
0
0
0
0
0
0
62
8
62
0
0
% K
% Leu:
0
0
0
0
0
31
16
0
0
0
0
0
0
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% N
% Pro:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% P
% Gln:
0
0
0
8
0
0
0
0
8
0
0
16
0
0
8
% Q
% Arg:
8
85
0
0
0
0
0
0
0
0
0
0
8
0
0
% R
% Ser:
0
0
0
0
8
0
0
8
8
0
0
0
16
16
16
% S
% Thr:
8
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% T
% Val:
0
0
77
0
0
24
0
0
8
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
31
0
8
0
0
0
16
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _